Master Thesis Project: Cell-Based Production of Native Compounds.

Project: Master Thesis Project

Location: Copenhagen, Denmark

Start: September, 2026

About us: In the medical field there are certain essential biologics that are impossible to synthesize due to their structural complexity. Animals have been the soul source of these compounds for decades. This has historically caused supply limitations, introduced variability, and raised ethical and sustainability concerns. Gephion Bio exists to solve that. We are developing a cell-based biomanufacturing platform that aims to improve the sourcing of the native compounds to make the process more consistent, scalable, and resilient.

Position overview: We are offering a master's thesis project to a highly motivated student with interests in stem cell biology and differentiation. The project aims to optimize a scalable directed differentiation protocol of livestock pluripotent stem cells. The characterization of cell identity across differentiation stages will consist of both wet-lab and bioinformatics approaches.

Depending on the needs of the project at the time of starting the master’s thesis work, the student will be involved in some of the following:

  • Culturing and maintaining livestock PSCs and derived differentiated cell populations

  • Optimization pre-differentiation conditions, such as seed-train cell expansion

  • Conducting adherent and suspension culture differentiation protocols to drive lineage commitment

  • Characterizing of pluripotency and differentiation outcomes using immunocytochemistry, flow cytometry, and bulk RNA sequencing

  • Quantifying compound yield across differentiation conditions using relevant analytical methods

  • Contributing to the optimization of differentiation conditions in an iterative, hypothesis-driven manner

We are looking for a student who:

  • Is currently enrolled in a master's program in molecular biology, biotechnology, cell biology, or a related discipline

  • Has at least 3 months of hands-on experience with mammalian cell culture (must-have), preferably with PSCs.

  • Is familiar with standard molecular and cell biology techniques such as ICC, flow cytometry, or qPCR

  • Is methodical, detail-oriented, and curious about working in a fast-paced research environment

What We Offer:

🌍 A thesis project with real-world applications

👩‍🔬 Mentorship from scientists with extensive stem cell biology expertise

🚀 Experiences in a dynamic biotech startup environment

🥳 Socials with your colleagues

Deadline: We evaluate applications on a rolling basis, so we encourage you to apply as soon as possible — the position will close once filled.

Interested? Send your CV together with a brief description of your motivation and relevant experience to contact@gephion.bio. We are excited to hear from you!